The Foundation for Research and Technology – Hellas (FORTH) is one of the largest research centres of Greece, with well organised facilities and a highly qualified staff. It is a private non profit research organization that operates under the supervision of the Greek Ministry of Development. The Institute of Computer Science at FORTH (FORTH-ICS), since its establishment in 1983, is a pioneering contributor towards the deployment and adoption of Information Society Technologies in Greece. FORTH-ICS has a relatively long history and recognized tradition in conducting basic and applied research, developing applications and products, providing services, and playing a leading role in Greece and internationally. The research activities of the BMI Laboratory focus on the development of innovative computer methods and tools in the area of biomedical informatics, medical imaging and bioinformatics. Research in machine learning and data mining for biomedical knowledge discovery, is an additional important activity of the Laboratory.